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It chemically related to opiates. Ultram should not be stopped without consulting his doctor. A seizure while taking Tramadol. When he stops taking the drug. Never be given to another person, especially someone who has a history of seizures. A seizure while taking Tramadol. If a patient abuses painkillers for a period of time, he can become addicted to the drug and experience withdrawal symptoms when he stops taking the drug.